ABOMB

Set to 18 different clues across 18 published puzzles, most often “Cloud maker” — The New York Times, Friday, 10 June 2011.

5 letters

Every clue on record, most used first

Cloud makeronce
The New York Times — Friday, 10 June 2011
Big blast maker, for shortonce
The New York Times — Wednesday, 25 August 2010
W.W. II-ending weapon, for shortonce
The New York Times — Monday, 8 June 2009
Focus of the Manhattan Project, brieflyonce
The New York Times — Tuesday, 7 October 2008
Manhattan Project resultonce
The New York Times — Wednesday, 5 September 2007
Weapon in 1940s headlinesonce
The New York Times — Wednesday, 30 May 2007
Mushroom makeronce
The New York Times — Wednesday, 19 July 2006
1945 news, in headlinesonce
The New York Times — Sunday, 21 May 2006
"Little Boy" in 8/6/45 newsonce
The New York Times — Wednesday, 12 January 2005
Big news in 1945, informallyonce
The New York Times — Saturday, 18 December 2004
Mushroom cloud makeronce
The New York Times — Monday, 12 July 2004
Nuclear weapon, in old headlinesonce
The New York Times — Monday, 28 July 2003