CAVAE

Set to 2 different clues across 2 published puzzles, most often “Venae ___ (major blood vessels)” — The New York Times, Thursday, 17 January 2008.

5 letters

Every clue on record, most used first

Venae ___ (major blood vessels)once
The New York Times — Thursday, 17 January 2008
Venae ___once
The New York Times — Sunday, 1 August 1999