Filed from 8 published puzzles

CHAFE

Set to 6 different clues across 8 published puzzles, most often “Rub raw” — The New York Times, Monday, 2 July 2007.

5 letters

Every clue on record, most used first

Rub raw2 times
The New York Times — Monday, 2 July 2007
Rub the wrong way2 times
The New York Times — Sunday, 24 June 2007
Make soreonce
The New York Times — Sunday, 25 June 2006
Overstarched collar problemonce
The New York Times — Wednesday, 24 October 2001
Irritateonce
The New York Times — Saturday, 14 March 1998
Rub the wrong way?once
The New York Times — Wednesday, 23 July 1997

Other answers to these clues

BOTHER6 letters
GALL4 letters
GRATE5 letters
INCENSE7 letters
IRK3 letters
NETTLE6 letters
PESTER6 letters
PIQUE5 letters
RANKLE6 letters
RASP4 letters
RILE4 letters
ROIL4 letters