Filed from 3 published puzzles

CHIEFLY

Set to 2 different clues across 3 published puzzles, most often “In the main” — The New York Times, Sunday, 13 August 2006.

7 letters

Every clue on record, most used first

In the main2 times
The New York Times — Sunday, 13 August 2006
For the most partonce
The New York Times — Wednesday, 13 January 1999

Other answers to these clues

ASARULE7 letters
ATSEA5 letters
INGENERAL9 letters
MOSTLY6 letters
USUALLY7 letters