CLOT

Set to 22 different clues across 26 published puzzles, most often “Coagulate” — The New York Times, Monday, 17 November 2008.

4 letters

Every clue on record, most used first

Coagulate4 times
The New York Times — Monday, 17 November 2008
Thrombus2 times
The New York Times — Saturday, 16 May 1998
Medical condition treated by thrombolysisonce
The New York Times — Wednesday, 8 December 2010
Blood circulation problemonce
The New York Times — Monday, 19 April 2010
Arterial blockageonce
The New York Times — Monday, 1 January 2007
Thrombosis causeonce
The New York Times — Tuesday, 10 October 2006
Stick togetheronce
The New York Times — Saturday, 24 June 2006
Congealmentonce
The New York Times — Tuesday, 15 March 2005
Setonce
The New York Times — Sunday, 21 November 2004
Blood problemonce
The New York Times — Monday, 26 July 2004
Clusteronce
The New York Times — Thursday, 13 March 2003
Flow stopperonce
The New York Times — Wednesday, 31 July 2002