DECON

Set to 2 different clues across 2 published puzzles, most often “Purification process, briefly” — The New York Times, Friday, 2 May 2008.

5 letters

Every clue on record, most used first

Purification process, brieflyonce
The New York Times — Friday, 2 May 2008
Radioactivity cleanup process, for shortonce
The New York Times — Wednesday, 20 August 2003