ESTROGEN
Set to 3 different clues across 3 published puzzles, most often “Ovary secretion” — The New York Times, Sunday, 1 December 2002.
8 letters
Every clue on record, most used first
- Ovary secretiononce
The New York Times — Sunday, 1 December 2002
- Female hormoneonce
The New York Times — Monday, 1 April 1996
- Ovarian productonce
The New York Times — Saturday, 3 December 1994