ITI

Set to 7 different clues across 23 published puzzles, most often "Lord, is ___?" — The New York Times, Thursday, 4 August 2011.

3 letters

Every clue on record, most used first

"Lord, is ___?"13 times
The New York Times — Thursday, 4 August 2011
"Is ___?"3 times
The New York Times — Saturday, 3 July 2010
"Is ___, Lord?"2 times
The New York Times — Thursday, 29 March 2007
"Lord, is ___?": Matthew2 times
The New York Times — Saturday, 17 September 2005
"That's ___ quit!"once
The New York Times — Friday, 5 February 2010
"And another said, Is ___?": Mark 14:19once
The New York Times — Saturday, 4 December 2004
"Lord, is ___?": Matt. 26:22once
The New York Times — Saturday, 13 November 1999