LEON

Set to 46 different clues across 64 published puzzles, most often “Ponce de ___” — The New York Times, Monday, 28 May 2007.

4 letters

Every clue on record, most used first

Ponce de ___5 times
The New York Times — Monday, 28 May 2007
Revolutionary Trotsky4 times
The New York Times — Sunday, 5 December 2004
Nicaragua's second-largest city3 times
The New York Times — Saturday, 8 July 2006
Old Spanish kingdom3 times
The New York Times — Wednesday, 26 April 2000
Singer Redbone2 times
The New York Times — Sunday, 1 January 2006
City NNW of Madrid2 times
The New York Times — Sunday, 16 October 2005
Boxer Spinks2 times
The New York Times — Thursday, 24 June 2004
Writer Uris2 times
The New York Times — Monday, 20 October 2003
Clinton aide Panetta2 times
The New York Times — Tuesday, 4 December 2001
Former capital of Nicaragua2 times
The New York Times — Thursday, 9 August 2001
Panetta of the White House2 times
The New York Times — Thursday, 8 June 1995
Provincial capital NW of Madridonce
The New York Times — Friday, 29 April 2011