LOCALANESTHESIA

Set to 2 different clues across 2 published puzzles, most often “It's not a total knockout” — The New York Times, Saturday, 18 October 2008.

15 letters

Every clue on record, most used first

It's not a total knockoutonce
The New York Times — Saturday, 18 October 2008
It may be used in minor surgeryonce
The New York Times — Tuesday, 28 October 1997