MALARIA
Set to 3 different clues across 4 published puzzles, most often “Tropical woe” — The New York Times, Wednesday, 30 January 2008.
7 letters
Every clue on record, most used first
- Tropical woe2 times
The New York Times — Wednesday, 30 January 2008
- Sub-Saharan scourgeonce
The New York Times — Saturday, 14 January 2006
- "Bad air," literallyonce
The New York Times — Sunday, 15 September 1996