Filed from 4 published puzzles

MUTATE

Set to 4 different clues across 4 published puzzles, most often “Change genetically” — The New York Times, Sunday, 9 March 2008.

6 letters

Every clue on record, most used first

Change geneticallyonce
The New York Times — Sunday, 9 March 2008
Changeonce
The New York Times — Friday, 14 December 2007
What a gene might doonce
The New York Times — Thursday, 18 November 2004
Change dramaticallyonce
The New York Times — Thursday, 23 September 2004

Other answers to these clues

AFFECT6 letters
ALTER5 letters
AMEND5 letters
CHUMP5 letters
EMEND5 letters
OIL3 letters
REDO4 letters
REPLACE7 letters