PROXIMA

Set to 2 different clues across 2 published puzzles, most often “Nearest, to Nero” — The New York Times, Saturday, 16 February 2008.

7 letters

Every clue on record, most used first

Nearest, to Neroonce
The New York Times — Saturday, 16 February 2008
___ Centauri (closest star to the sun)once
The New York Times — Wednesday, 30 May 2001